Collaboration Opportunities
MicroBiopharm Japan Co., Ltd. (hereinafter referred to as "MBJ") regards external partnerships as a useful opportunity to generate synergy for more value to all stakeholders in the industry.
Active Collaboration Case with Customers
Case 1: 
Contract Manufacturing of Fermentation Products
1) Conclusion of contract manufacturing agreement with a company selling a product obtained by fermentation
2) Further improvement of productivity and quality after start of manufacturing and proposing a better product production method to the customer
Technical Transfer
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
Process ImprovementEstablishment of an efficient production system for target compounds by fermentation technology
| Partner | 
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|---|---|
| MBJ | 
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Contract ManufacturingSupplying fermentation products
| Partner | |
|---|---|
| MBJ | 
 | 
*MBJ has many experiences on contract manufacturing with domestic and overseas companies, 
including  drug substances/intermediates, food additives, pesticides, and chemical products.
Case 2: 
ADC Drug Discovery Service
1) ez-ADiCon™ (ADC conjugation technology based on MBJ's original enzymes) for drug discovery support and sample preparation
2) ez-ADiCon™ available for licensing
Drug Discovery SupportVerification of novel ADC synthesis with MBJ's conjugation technology
Sample preparation
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
LicensingProviding ADC conjugation technology
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
Case 3: 
Enzyme Improvement for Bioconversion
1) Conclusion of contract research agreement on process improvement. Collaborator has a trouble on crystallization step due to by-products
2) Improvement of enzyme to remove side reactions with our technology on contract research
3) Trial manufacturing for practical use
Technology Transfer
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
Contract ResearchEnzyme improvement
| Partner | 
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|---|---|
| MBJ | 
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Practical Application Study
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
* MBJ has a large number of experiences in contract research and manufacturing 
from pharmaceutical and food manufacturers.
Case 4: 
Development of New Drugs and Products 
-Supplying Microbial Products to Customers-
1) MBJ provides its own extracts of isolated bacteria to partners
2) Partners seek for the case they find substances that can be candidates of pharmaceuticals and new products
3) Based on partners request, MBJ provides the substances produced by microorganisms (the productivity is raised with traditional and genetical strain improvement techniques and the process is established for the commercial production)
Drug Discovery SupportDiscovery of drug and new product candidates from microbial extracts
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
Contract Development WorkEfficient production of candidate compounds by fermentation technology
| Partner | 
 | 
|---|---|
| MBJ | 
 | 
Contract ManufacturingClinical trials with the compounds
| Partner | 
 | 
|---|---|
| MBJ | 
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* MBJ is cooperating with a number of major pharmaceutical and agrochemical manufacturers.


